USE OF PHYSICOCHEMICAL PARAMETERS IN DISTANCE GEOMETRY AND RELATED 3-DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIPS - A DEMONSTRATION USING ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE INHIBITORS

被引：66
|
作者：
GHOSE, AK [1 ]
CRIPPEN, GM [1 ]
机构：
[1] TEXAS A&M UNIV,DEPT CHEM,COLLEGE STN,TX 77843
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1985年 / 28卷 / 03期
关键词：
D O I：
10.1021/jm00381a013
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：333 / 346
页数：14
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