METHOTREXATE CONCENTRATION LEVELS IN THE CEREBROSPINAL-FLUID DURING HIGH-DOSE METHOTREXATE INFUSIONS - AN UNRELIABLE PREDICTION

被引：30

作者：

LIPPENS, RJJ ^{[1
]}

WINOGRAD, B ^{[1
]}

机构：

[1] UNIV HOSP NIJMEGEN,DEPT CLIN PHARM,6500 HB NIJMEGEN,NETHERLANDS

来源：

PEDIATRIC HEMATOLOGY AND ONCOLOGY | 1988年 / 5卷 / 02期

关键词：

D O I：

10.3109/08880018809031261

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：115 / 124

页数：10

共 21 条

[1] INTRATHECAL METHOTREXATE VERSUS CENTRAL NERVOUS-SYSTEM LEUKEMIA [J].

BLEYER, WA .

CANCER DRUG DELIVERY, 1984, 1 (02) :157-167

[2]

COLLS BM, 1983, CANCER CHEMOTH PHARM, V11, P188

[3] HIGH-DOSE METHOTREXATE AS PART OF REMISSION MAINTENANCE THERAPY FOR CHILDHOOD ACUTE LYMPHOCYTIC-LEUKEMIA - A PEDIATRIC ONCOLOGY GROUP PILOT-STUDY [J].

FRANKEL, LS ;

WANG, YM ;

SHUSTER, J ;

NITSCHKE, R ;

DOERING, EJ ;

PULLEN, J .

JOURNAL OF CLINICAL ONCOLOGY, 1983, 1 (12) :804-809

[4]

Freeman A I, 1979, Haematol Blood Transfus, V23, P115

[5]

GILCHRIST NL, 1985, CANCER CHEMOTH PHARM, V15, P290

[6]

HRYNIUK WM, 1969, MOL PHARMACOL, V5, P557

[7]

KIMMELBERG HK, 1978, J NEUROSURG, V48, P883

[8] CHANGE IN TRANSFER RATE OF METHOTREXATE FROM SPINAL-FLUID TO PLASMA DURING INTRATHECAL THERAPY IN CHILDREN AND ADULTS [J].

LANKELMA, J ;

LIPPENS, RJJ ;

DRENTHESCHONK, A ;

TERMOND, EFS ;

VANDERKLEIJN, E .

CLINICAL PHARMACOKINETICS, 1980, 5 (05) :465-475

[9] DETERMINATION OF METHOTREXATE IN PLASMA BY ON-COLUMN CONCENTRATION AND ION-EXCHANGE CHROMATOGRAPHY [J].

LANKELMA, J ;

POPPE, H .

JOURNAL OF CHROMATOGRAPHY, 1978, 149 (FEB) :587-598

[10]

LIPPENS RJJ, 1984, AM J PEDIAT HEMATOL, V6, P397

← 1 2 3 →