Prevalence of metallo-beta-lactamase producing Pseudomonas aeruginosa and Acinetobacter species in intensive care areas in a tertiary care hospital

被引：28
作者：
De, Anuradha S. [1 ]
Kumar, Simit H. [1 ]
Baveja, Sujata M. [1 ]
机构：
[1] LTM Med Coll, Dept Microbiol, Bombay 400022, Maharashtra, India
来源：
INDIAN JOURNAL OF CRITICAL CARE MEDICINE | 2010年 / 14卷 / 04期
关键词：
MBL producers; ICUs;
D O I：
10.4103/0972-5229.76089
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A total of 39 non-duplicate isolates of carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter species isolated from blood and endotracheal secretions were tested for metallo-beta-lactamase (MBL) production by modifi ed-EDTA disc synergy and double disc synergy tests. The prevalence of MBLs was 33.33% by both the above tests. All patients with MBL-positive isolates were multidrug resistant and had multiple risk factors like > 8 days hospital stay, catheterization, IV lines, previous antibiotic use, etc. These were risk factors for imipenem resistance also. The overall mortality in MBL-positive patients was 46.15%.
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收藏
页码：217 / 219
页数：3
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