OUTCOME AFTER STEREOTAXIC THALAMOTOMY FOR DYSTONIA AND HEMIBALLISMUS

被引:103
作者
CARDOSO, F
JANKOVIC, J
GROSSMAN, RG
HAMILTON, WJ
机构
[1] BAYLOR COLL MED,CTR PARKINSONS DIS,DEPT NEUROL,HOUSTON,TX 77030
[2] BAYLOR COLL MED,DEPT NEUROSURG,HOUSTON,TX 77030
关键词
DYSTONIA; HEMIBALLISMUS; STEREOTAXY; THALAMOTOMY;
D O I
10.1227/00006123-199503000-00009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
THE OUTCOME AFTER single or staged stereotactic thalamotomies in 17 patients with dystonia and 2 patients with hemiballismus is reviewed. All patients were severely disabled by their movement disorders despite optimal pharmacological therapies. Eight of the patients with dystonia (47%) showed moderate improvement immediately after the procedures. Six of these eight patients maintained their improvement, and two other patients with dystonia improved significantly, during the follow-up period (mean, 37.6 mo). The long-term outcome was better in patients with secondary dystonia (50% moderately or markedly improved at a mean of 41.0 mo) than in patients with primary dystonia (43% moderately or markedly improved at a mean of 32.9 mo). Excellent control was achieved in both of the patients who underwent thalamotomies for hemiballismus.
引用
收藏
页码:501 / 507
页数:7
相关论文
共 18 条
[1]   THE FUNCTIONAL-ANATOMY OF BASAL GANGLIA DISORDERS [J].
ALBIN, RL ;
YOUNG, AB ;
PENNEY, JB .
TRENDS IN NEUROSCIENCES, 1989, 12 (10) :366-375
[2]   STEREOTAXIC THALAMOTOMY IN 55 CASES OF DYSTONIA [J].
ANDREW, J ;
FOWLER, CJ ;
HARRISON, MJG .
BRAIN, 1983, 106 (DEC) :981-1000
[3]   TORSION DYSTONIA - A DOUBLE-BLIND, PROSPECTIVE TRIAL OF HIGH-DOSAGE TRIHEXYPHENIDYL [J].
BURKE, RE ;
FAHN, S ;
MARSDEN, CD .
NEUROLOGY, 1986, 36 (02) :160-164
[4]  
Cooper IS, 1976, DYSTONIA ADV NEUROLO, P423
[5]   HIGH DOSAGE ANTICHOLINERGIC THERAPY IN DYSTONIA [J].
FAHN, S .
NEUROLOGY, 1983, 33 (10) :1255-1261
[6]  
GREENE P, 1988, DYSTONIA, V2, P547
[7]  
GROS C, 1976, NEUROCHIRURGIA, V19, P171
[8]  
GROSSMAN RG, 1993, PARKINSONS DISEASE M, P531
[9]   THERAPEUTIC USES OF BOTULINUM TOXIN [J].
JANKOVIC, J ;
BRIN, MF .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (17) :1186-1194
[10]  
LEVESQUE MF, 1992, STEREOT FUNCT NEUROS, V58, P88