Informed metabolic engineering of oil crops using control analysis

被引：4

作者：

Ramli, Umi S. ^{[1
]}

Tang, Mingguo ^{[1
]}

Quant, Patti A. ^{[2
]}

Guschina, Irina A. ^{[1
]}

Fawcett, Tony ^{[3
]}

Harwood, John L. ^{[1
]}

机构：

[1] Cardiff Univ, Sch Biosci, Cardiff CF10 3AX, Wales

[2] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England

[3] Univ Durham, Dept Biol Sci, Durham DH1 3LE, England

来源：

BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY | 2014年 / 3卷 / 01期

基金：

英国生物技术与生命科学研究理事会;

关键词：

Oil crops; Triacylglycerol accumulation; Regulation of oil synthesis; Metabolic control analysis;

D O I：

10.1016/j.bcab.2013.12.001

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Oil crops are a very important agricultural commodity. Demand for such oils is rising steadily (at more than 5% per year over the last half century). Although the majority of plant oils are used for food or animal feed, there is increasing interest in their use as renewable chemicals for industry. Because of the demonstrated demand for oils and finite agricultural land, attention is focussing on improving productivity. Genetic manipulation of crop plants needs a knowledge of the biosynthetic pathways concerned and how they are regulated. Although there are different ways to acquire much information, metabolic flux and metabolic control analyses are ways to provide quantitative assessments. In this review we describe our experiments using metabolic control analysis on important crops - oil palm, oilseed rape, olive and soybean. Such research provides information for future informed genetic manipulations and we give a successful example of this in oilseed rape (Brassica napes L.). (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：49 / 52

页数：4

共 33 条

[21] Control mechanisms operating for lipid biosynthesis differ in oil-palm (Elaeis guineensis Jacq.) and olive (Olea europaea L.) callus cultures [J].