Osteosarcoma: a comprehensive review

被引:383
作者
Misaghi, Amirhossein [1 ]
Goldin, Amanda [1 ]
Awad, Moayd [1 ,2 ]
Kulidjian, Anna A. [1 ]
机构
[1] Univ Calif San Diego, Dept Orthopaed Surg, San Diego, CA 92103 USA
[2] Univ Jeddah, Sch Med, Jeddah, Saudi Arabia
关键词
Osteosarcoma; Review; Oncology; Sarcoma; Tumor;
D O I
10.1051/sicotj/2017028
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Osteosarcoma (OS) is a relatively rare tumor of bone with a worldwide incidence of 3.4 cases per million people per year. For most of the twentieth century, five-year survival rates for classic OS were very low. In the 1970s, the introduction of adjuvant chemotherapy in the treatment of OS increased survival rates dramatically. The current article reviews the various types of OS and analyzes the clinical and histological features. We also examine historical and current literature to present a succinct review of methods for diagnosis and staging, as well as treatment, and we also discuss some of the future directions of treatment.
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页数:8
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