ISOLATION AND STRUCTURES OF AN ANTIFUNGAL ANTIBIOTIC, FUSARIELIN-A, AND RELATED-COMPOUNDS PRODUCED BY A FUSARIUM SP

被引：82
作者：
KOBAYASHI, H
SUNAGA, R
FURIHATA, K
MORISAKI, N
IWASAKI, S
机构：
[1] UNIV TOKYO,INST MOLEC & CELLULAR BIOSCI,BUNKYO KU,TOKYO 113,JAPAN
[2] UNIV TOKYO,DEPT AGR CHEM,BUNKYO KU,TOKYO 113,JAPAN
来源：
JOURNAL OF ANTIBIOTICS | 1995年 / 48卷 / 01期
关键词：
D O I：
10.7164/antibiotics.48.42
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A new antifungal antibiotic, fusarielin A, and three related compounds, fusarielins B, C and D, were obtained from a culture of a Fusarium sp. The skeletal structure and the relative stereochemistry of fusarielin A were determined mainly on the basis of its NMR data, and the absolute structure was elucidated by using the exciton chirality method and the modified Mosher method. The structures of the other homologues were determined by comparison of their spectral data with those of fusarielin A.
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页码：42 / 52
页数：11
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