SYNTHESIS OF C-11 LABELED (R)-CARNITINE

被引:2
作者
HOLSCHBACH, M
HAMKENS, W
RODEN, W
FEINENDEGEN, LE
机构
[1] Institute of Medicine Research Center, Jülich, D-5170
关键词
C-11-LABELED CARNITINE; VITAMIN-BT; SYNTHESIS; POSITRON; EMISSION TOMOGRAPHY (PET);
D O I
10.1002/jlcr.2580290512
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A route to C-11-labelled (R)-carnitine (1), based on the methylation of the dimethyl derivative (2) is described. Furthermore, a five-step synthesis for the enantiomerically pure precursor (2) is outlined.
引用
收藏
页码:599 / 606
页数:8
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