A TRANSGENIC IMMUNOGLOBULIN-MU GENE PREVENTS REARRANGEMENT OF ENDOGENOUS GENES

被引：188
作者：
WEAVER, D
COSTANTINI, F
IMANISHIKARI, T
BALTIMORE, D
机构：
[1] COLUMBIA UNIV COLL PHYS & SURG,DEPT HUMAN GENET & DEV,NEW YORK,NY 10032
[2] MIT,DEPT BIOL,CAMBRIDGE,MA 02139
[3] MIT,CTR CANC RES,CAMBRIDGE,MA 02139
来源：
CELL | 1985年 / 42卷 / 01期
关键词：
D O I：
10.1016/S0092-8674(85)80107-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：117 / 127
页数：11
相关论文
共 36 条
  • [1] ORGANIZATION AND REORGANIZATION OF IMMUNOGLOBULIN GENES IN A-MULV TRANSFORMED-CELLS - REARRANGEMENT OF HEAVY BUT NOT LIGHT CHAIN GENES
    ALT, F
    ROSENBERG, N
    LEWIS, S
    THOMAS, E
    BALTIMORE, D
    [J]. CELL, 1981, 27 (02) : 381 - 390
  • [2] SYNTHESIS OF SECRETED AND MEMBRANE-BOUND IMMUNOGLOBULIN-MU HEAVY-CHAINS IS DIRECTED BY MESSENGER-RNAS THAT DIFFER AT THEIR 3' ENDS
    ALT, FW
    BOTHWELL, ALM
    KNAPP, M
    SIDEN, E
    MATHER, E
    KOSHLAND, M
    BALTIMORE, D
    [J]. CELL, 1980, 20 (02) : 293 - 301
  • [3] ACTIVITY OF MULTIPLE LIGHT CHAIN GENES IN MURINE MYELOMA CELLS PRODUCING A SINGLE, FUNCTIONAL LIGHT CHAIN
    ALT, FW
    ENEA, V
    BOTHWELL, ALM
    BALTIMORE, D
    [J]. CELL, 1980, 21 (01) : 1 - 12
  • [4] ORDERED REARRANGEMENT OF IMMUNOGLOBULIN HEAVY-CHAIN VARIABLE REGION SEGMENTS
    ALT, FW
    YANCOPOULOS, GD
    BLACKWELL, TK
    WOOD, C
    THOMAS, E
    BOSS, M
    COFFMAN, R
    ROSENBERG, N
    TONEGAWA, S
    BALTIMORE, D
    [J]. EMBO JOURNAL, 1984, 3 (06) : 1209 - 1219
  • [5] ALT FW, 1982, MOL CELL BIOL, V2, P286
  • [6] BERGMAN Y, 1983, J IMMUNOL, V131, P1876
  • [7] ORGANIZATION OF 4 MOUSE LAMBDAL-LIGHT CHAIN IMMUNOGLOBULIN GENES
    BLOMBERG, B
    TRAUNECKER, A
    EISEN, H
    TONEGAWA, S
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (06): : 3765 - 3769
  • [8] HEAVY-CHAIN VARIABLE REGION - MULTIPLE GENE SEGMENTS ENCODE ANTI-4-(HYDROXY-3-NITROPHENYL)ACETYL IDIOTYPIC ANTIBODIES
    BOERSCHSUPAN, ME
    AGARWAL, S
    WHITESCHARF, ME
    IMANISHIKARI, T
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1985, 161 (06) : 1272 - 1292
  • [9] HEAVY-CHAIN VARIABLE REGION CONTRIBUTION TO THE NPB FAMILY OF ANTIBODIES - SOMATIC MUTATION EVIDENT IN A GAMMA-2A VARIABLE REGION
    BOTHWELL, ALM
    PASKIND, M
    RETH, M
    IMANISHIKARI, T
    RAJEWSKY, K
    BALTIMORE, D
    [J]. CELL, 1981, 24 (03) : 625 - 637
  • [10] EXPRESSION OF A MICROINJECTED IMMUNOGLOBULIN GENE IN THE SPLEEN OF TRANSGENIC MICE
    BRINSTER, RL
    RITCHIE, KA
    HAMMER, RE
    OBRIEN, RL
    ARP, B
    STORB, U
    [J]. NATURE, 1983, 306 (5941) : 332 - 336
1234