STEREOCONTROLLED ROUTES TO DERIVATIVES OF 3-ALKOXYCARBONYL-2-AMINO-4-ARYL-5-CYANO-6-PHENYL-4H-PYRANS

被引：16

作者：

MARTIN, N ^{[1
]}

MARTINEZGRAU, A ^{[1
]}

SEOANE, C ^{[1
]}

MARCO, JL ^{[1
]}

机构：

[1] CSIC,INST QUIM ORGAN GEN,E-28006 MADRID,SPAIN

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 01期

关键词：

D O I：

10.1016/0957-4166(94)00382-L

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The asymmetric Michael addition of cyanoacetates 2b-e and benzoylacetonitrile 6 to alpha-benzoylcinnamonitrile 3 and alpha-cyanocinnamates 7b-e, respectively, has been studied. The resulting 3-alkoxycarbonyl-2-amino-4-aryl-5-cyano-6-phenyl-4H-pyrans 4b-e have been obtained in moderate diastereomeric excess and good chemical yield.

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页码：255 / 262

页数：8

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