Bone Marrow Micrometastases in Breast Cancer Patients: A Long-Term Follow-up Study

被引：0

作者：

Molino, Annamaria ^{[1
]}

Giovannini, Monica ^{[2
]}

Micciolo, Rocco ^{[3
]}

Auriemma, Alessandra ^{[1
]}

Fiorio, Elena ^{[1
]}

Santo, Antonio ^{[1
]}

Cetto, Gian Luigi ^{[1
]}

机构：

[1] Univ Verona, Dept Med Oncol, Verona, Italy

[2] Osped San Raffaele, Dept Med Oncol, Milan, Italy

[3] Univ Trento, Inst Stat, Trento, Italy

来源：

CLINICAL MEDICINE INSIGHTS-ONCOLOGY | 2008年 / 2卷

关键词：

bone marrow; breast cancer; long-term follow-up; micrometastases;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In 125 early breast cancer patients who underwent multiple bone marrow aspirates, there was no significant difference in terms of disease-free and overall survival after a median follow-up of 163 months between the patients with or without micrometastasis at the time of primary surgery. However, when the time-dependent evolution of the bone marrow aspirates was taken into account, some evidence for a longer disease-free and overall survival was found for the patients with negative bone marrow

引用

页码：487 / 490

页数：4

共 34 条

[1]

American Society of Clinical Oncology, 1997, REC BREAST CANC SURV, V15, P2149

[2]

Andersen P., 1982, COXS REGRESSION MODE

[3] Real- time RT-PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer [J].

Benoy, IH ;

Elst, H ;

Philips, M ;

Wuyts, H ;

Van Dam, P ;

Scharpé, S ;

Van Marck, E ;

Vermeulen, PB ;

Dirix, LY .

BRITISH JOURNAL OF CANCER, 2006, 94 (05) :672-680

[4] Prognostic significance of disseminated tumor cells as detected by quantitative real-time reverse-transcriptase polymerase chain reaction in patients with breast cancer [J].

Benoy, Ina H. ;

Elst, Hilde ;

Philips, Marita ;

Wuyts, Hilde ;

Van Dam, Peter ;

Scharpe, Simon ;

Van Marck, Eric ;

Vermeulen, Peter B. ;

Dirix, Luc Y. .

CLINICAL BREAST CANCER, 2006, 7 (02) :146-152

[5]

BERGER U, 1988, AM J CLIN PATHOL, V90, P1

[6] A pooled analysis of bone marrow micrometastasis in breast cancer [J].

Braun, S ;

Vogl, FD ;

Naume, B ;

Janni, W ;

Osborne, MP ;

Coombes, RC ;

Schlimok, G ;

Diel, IJ ;

Gerber, B ;

Gebauer, G ;

Pierga, JY ;

Marth, C ;

Oruzio, D ;

Wiedswang, G ;

Solomayer, EF ;

Kundt, G ;

Strobl, B ;

Fehm, T ;

Wong, GYC ;

Bliss, J ;

Vincent-Salomon, A ;

Pantel, K .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (08) :793-802

[7] PREDICTION OF EARLY RELAPSE IN PATIENTS WITH OPERABLE BREAST-CANCER BY DETECTION OF OCCULT BONE-MARROW MICROMETASTASES [J].

COTE, RJ ;

ROSEN, PP ;

LESSER, ML ;

OLD, LJ ;

OSBORNE, MP .

JOURNAL OF CLINICAL ONCOLOGY, 1991, 9 (10) :1749-1756

[8]

COTE RJ, 1991, DIAGN ONCOL, V1, P37

[9]

COX DR, 1972, J R STAT SOC B, V34, P187

[10] MICROMETASTASES IN BREAST-CANCER - LONG-TERM FOLLOW-UP OF THE 1ST PATIENT COHORT [J].

DEARNALEY, DP ;

ORMEROD, MG ;

SLOANE, JP .

EUROPEAN JOURNAL OF CANCER, 1991, 27 (03) :236-239

← 1 2 3 4 →