INVOLVEMENT OF SAPECIN IN EMBRYONIC-CELL PROLIFERATION OF SARCOPHAGA-PEREGRINA (FLESH FLY)

被引：30

作者：

KOMANO, H ^{[1
]}

HOMMA, K ^{[1
]}

NATORI, S ^{[1
]}

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

来源：

FEBS LETTERS | 1991年 / 289卷 / 02期

关键词：

SAPECIN; GROWTH FACTOR; EMBRYONIC CELL; SARCOPHAGA-PEREGRINA;

D O I：

10.1016/0014-5793(91)81061-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Addition of antibodies against sapecin to the culture medium of NIH-Sape-4 cells derived from a Sarcophaga embryo greatly inhibited cell proliferation, whereas addition of sapecin stimulated cell proliferation. These results suggest that sapecin is involved in the proliferation of embryonic cells of Sarcophaga. Sapecin is known to have potent antibacterial activity, so it seems to have two different biological functions: i.e. protection against bacterial infection and stimulation of embryonic cell proliferation.

引用

页码：167 / 170

页数：4

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