EARLY STIMULATION EFFECTS ON NOVELTY-INDUCED BEHAVIOR IN 2 PSYCHOGENETICALLY-SELECTED RAT LINES WITH DIVERGENT EMOTIONALITY PROFILES

被引：92

作者：

FERNANDEZTERUEL, A ^{[1
]}

ESCORIHUELA, RM ^{[1
]}

NUNEZ, JF ^{[1
]}

GOMA-I-FREIXANET, M ^{[1
]}

DRISCOLL, P ^{[1
]}

TOBENA, A ^{[1
]}

机构：

[1] LAB VERGLEICHENDE PHYSIOL & VERHALTENSBIOL, ZURICH, SWITZERLAND

来源：

NEUROSCIENCE LETTERS | 1992年 / 137卷 / 02期

关键词：

POSTNATAL HANDLING-STIMULATION; ENVIRONMENTAL ENRICHMENT; ACTIVITY; HEAD-DIPPING; EMOTIONAL REACTIVITY; ROMAN RAT LINE;

D O I：

10.1016/0304-3940(92)90400-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The present study shows that postnatal handling (H: consisting of removing the pups from the nest twice daily and placing them individually in plastic cages lined with paper towel for a period of 10 min, between postnatal days 1 and 21) and/or environmental enrichment (E: for a period of 6 months) of Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats induced long-lasting decreases in emotional reactivity (i.e. reduced defecations in the open field, OF, and hole-board, HB, tests) as well as increases in exploratory behavior (i.e. head-dipping) in a manner dependent upon the rat line (there were 'line x H' and 'line x E' interactions). It is reported for the first time that RHA/Verh rats show more head-dipping behavior than RLA/Verh rats, and that the environmental treatments can increase head-dipping of RLA/Verh animals to the level shown by RHA/Verh rats.

引用

页码：185 / 188

页数：4

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