BROP - A NEW REAGENT FOR COUPLING N-METHYLATED AMINO-ACIDS

被引：108

作者：

COSTE, J

DUFOUR, MN

PANTALONI, A

CASTRO, B

机构：

[1] Centre CNRS-INSERM de Pharmacologie Endocrinologie, 34094 Montpellier Cédex 2, Rue de la Cardonille

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)94598-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

BroP (bromo tris(dimethylamino) phosphonium hexafluorophosphate) is a particularly suitable reagent for coupling N-methylated amino acids. It is stable and gives very high yields in short reaction times. Dipeptides are obtained without appreciable epimerization. © 1990.

引用

页码：669 / 672

页数：4

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