A SIMPLE SYNTHESIS OF "1,3-DIALKYLPYRIDO[2,3-D]PYRIMIDINES

被引：13

作者：

ITOH, T

IMINI, T

OGURA, H

KAWAHARA, N

NAKAJIMA, T

WATANABE, KA

机构：

[1] HOKKAIDO INST PHARMACEUT SCI,OTARU 04702,JAPAN

[2] CORNELL UNIV,GRAD SCH MED SCI,SLOAN KETTERING DIV,SLOAN KETTERING INST CANC RES,NEW YORK,NY 10021

来源：

HETEROCYCLES | 1983年 / 20卷 / 11期

关键词：

D O I：

10.3987/R-1983-11-2177

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：2177 / 2180

页数：4

共 13 条

[1] DEVELOPMENT OF ETHYL 3,4-DIHYDRO-4-OXOPYRIMIDO[4,5-B]QUINOLINE-2-CARBOXYLATE, A NEW PROTOTYPE WITH ORAL ANTIALLERGY ACTIVITY [J].

ALTHUIS, TH ;

MOORE, PF ;

HESS, HJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (01) :44-48

[2]

ANDERSON GL, 1976, J ORG CHEM, V41, P1095

[3] ANTIHYPERTENSIVE ACTIVITY OF 6-ARYLPYRIDO[2,3-D]PYRIMIDIN-7-AMINE DERIVATIVES [J].

BENNETT, LR ;

BLANKLEY, CJ ;

FLEMING, RW ;

SMITH, RD ;

TESSMAN, DK .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (04) :382-389

[4] ANTIMALARIAL SUBSTANCES .26. FOLATE ANTAGONISTS .4. ANTIMALARIAL AND ANTIMETABOLITE EFFECTS OF 2,4-DIAMINO-6-[(BENZYL)AMINO]PYRIDO[2,3-D]-PYRIMIDINES [J].

DAVOLL, J ;

CLARKE, J ;

ELSLAGER, EF .

JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (08) :837-&

[5] SYNTHESIS AND ANTI-TUMOR ACTIVITY OF 2,4-DIAMINO-6-(2,5-DIMETHOXYBENZYL)-5-METHYLPYRIDO[2,3-D]PYRIMIDINE [J].

GRIVSKY, EM ;

LEE, S ;

SIGEL, CW ;

DUCH, DS ;

NICHOL, CA .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (03) :327-329

[6]

Hurbert B. S., 1968, J MED CHEM, V11, P711

[7]

Irwin W.J, 1969, ADVANCES HETROCYCLIC, V10, P149

[8]

KRETZSCHMAR E, 1980, PHARMAZIE, V35, P253

[9] PYRIDO[2,3-D)PYRIMIDINE ANTIBACTERIAL AGENTS .3. 8-ALKYL AND 8-VINYL-5,8-DIHYDRO-5-OXO-2-[1-PIPERAZINYL)PYRIDO[2,3-D)PYRIMIDINE-6-CARBOXYLIC ACIDS AND THEIR DERIVATIVES [J].

MATSUMOTO, J ;

MINAMI, S .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (01) :74-79

[10] THE APPLICATION OF THE HOFMANN REACTION TO THE SYNTHESIS OF HETEROCYCLIC COMPOUNDS .7. SYNTHESIS OF PYRIDINOPYRIMIDINE DERIVATIVES [J].

MCLEAN, AC ;

SPRING, FS .

JOURNAL OF THE CHEMICAL SOCIETY, 1949, (OCT) :2582-2585

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