The first example of second-harmonic generation (SHG) in an ion implanted KTiOPO4 waveguide is reported. This was formed by helium implantation, and SHG was achieved using zero order mode phase matching at lambda congruent-to 1.07-mu-m. The results indicate that the high nonlinearity remains in the guiding region after implantation. The conversion efficiency in the guide is estimated to be > 10% for approximately 1-mu-J 20 ns pulsed excitation.