VISUALIZATION OF ENANTIOMERS IN A POLYPEPTIDE LIQUID-CRYSTAL SOLVENT THROUGH C-13 NMR-SPECTROSCOPY

被引：60

作者：

LESOT, P

MERLET, D

MEDDOUR, A

COURTIEU, J

LOEWENSTEIN, A

机构：

[1] UNIV PARIS 11,ICMO,CHIM ORGAN STRUCT LAB,CNRS,F-91405 ORSAY,FRANCE

[2] TECHNION ISRAEL INST TECHNOL,DEPT CHEM,IL-32000 HAIFA,ISRAEL

来源：

JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS | 1995年 / 91卷 / 09期

关键词：

D O I：

10.1039/ft9959101371

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

High-resolution, proton-coupled and decoupled, carbon-13 NMR in natural abundance is used to observe the spectra of enantiomers in chiral molecules dissolved in the poly(gamma-benzyl-L-glutamate) (PBLG)/CD2Cl2 liquid-crystalline system. Discrimination between enantiomers can be obtained either through differences in their dipolar interactions or in their chemical shift anisotropies. This technique provides a new tool for the visualization of enantiomers and the measurement of the enantiomeric ratio. Several specific examples are presented and discussed.

引用

页码：1371 / 1375

页数：5

共 14 条

[1] ENZYMATIC RESOLUTION OF CYCLOPROPANOLS - AN EASY ACCESS TO OPTICALLY-ACTIVE CYCLOHEXANONES POSSESSING AN ALPHA-QUATERNARY CHIRAL CARBON [J].