POLYARTHROPATHY - A DELAYED-REACTION TO LOW-OSMOLALITY ANGIOGRAPHIC CONTRAST-MEDIUM IN PATIENTS WITH END-STAGE RENAL-DISEASE

被引：3
作者：
DONNELLY, PK
WILLIAMS, B
WATKIN, EM
机构：
[1] Department of Surgery, Leicester General Hospital, Leicester, LE5 4PW, Gwendolen Road
[2] Department of Nephrology, Leicester General Hospital, Leicester, LE5 4PW, Gwendolen Road
[3] Department of Radiology, Leicester General Hospital, Leicester, LE5 4PW, Gwendolen Road
来源：
EUROPEAN JOURNAL OF RADIOLOGY | 1993年 / 17卷 / 02期
关键词：
CONTRAST MEDIA; COMPLICATIONS; TOXICITY; KIDNEY; FAILURE;
D O I：
10.1016/0720-048X(93)90050-W
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Since the introduction of low osmolality non-ionic media, acute reactions to radiographic contrast are uncommon and delayed reactions are especially rare, consisting mostly of mild flu-like symptoms. We report two patients suffering from end-stage renal failure and treated by continuous ambulatory peritoneal dialysis (CAPD) who developed a severe constitutional illness including acute polyarthropathy 6 and 16 h after injection of the low osmolality non-ionic contrast medium, iopamidol. Although the clinical presentation of the reactions was similar to a systemic lupus syndrome there was no immunological evidence to support this as an aetiological mechanism. Since CAPD is a relatively inefficient method of clearing contrast media prolonged high circulating levels of iopamidol may have been a contributory factor to these unusually severe delayed contrast reactions.
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页码：130 / 132
页数：3
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