QUANTITATIVE AUTORADIOGRAPHY OF BETA-ADRENERGIC RECEPTORS IN RABBIT EYES

被引:15
作者
KAHLE, G
KAULEN, P
WOLLENSAK, J
机构
[1] Universitäts-Augenklinik im Klinikum Charlottenburg, Freie Universität Berlin, 1000 Berlin 19
关键词
ciliary body; eye; [!sup]125[!/sup]I]cyanopindolol; [!sup]3[!/sup]H]DHA; β-adrenergic receptor;
D O I
10.1016/0014-4835(90)90080-E
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Beta-adrenergic receptors were localized and quantified with autoradiographic methods in frozen sections of eyes of albino rabbits using [125I]cyanopindolol and [3H]dihydroalprenolol. Quantification in albino rabbits revealed highest β2-adrenoceptor densities in the ciliary body, the corneal epithelium and the corneal endothelium. Moreover, the iris showed significant amounts of specific binding, whereas the retina and sclera are nearly free of these receptors. © 1990.
引用
收藏
页码:503 / 507
页数:5
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