FATE OF AEROSOLIZED RECOMBINANT DNA-PRODUCED ALPHA-1-ANTITRYPSIN - USE OF THE EPITHELIAL SURFACE OF THE LOWER RESPIRATORY-TRACT TO ADMINISTER PROTEINS OF THERAPEUTIC IMPORTANCE

被引：74

作者：

HUBBARD, RC

CASOLARO, MA

MITCHELL, M

SELLERS, SE

ARABIA, F

MATTHAY, MA

CRYSTAL, RG

机构：

[1] NHLBI,PULM BRANCH,BLDG 10,ROOM 6D03,BETHESDA,MD 20892

[2] NHLBI,CARDIAC SURG BRANCH,BETHESDA,MD 20892

[3] UNIV CALIF SAN FRANCISCO,DEPT MED & PHYSIOL,CARDIOVASC RES INST,SAN FRANCISCO,CA 94143

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 02期

关键词：

D O I：

10.1073/pnas.86.2.680

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：680 / 684

页数：5

共 49 条

[1]

AUNGST BJ, 1988, J PHARMACOL EXP THER, V244, P23

[2]

BEATTY K, 1980, J BIOL CHEM, V255, P3931

[3]

BELL DY, 1981, AM REV RESPIR DIS, V124, P72

[4] ABSORPTION OF INTACT PROTEIN MOLECULES ACROSS PULMONARY AIR-TISSUE BARRIER [J].

BENSCH, KG ;

DOMINGUEZ, E ;

LIEBOW, AA .

SCIENCE, 1967, 157 (3793) :1204-+

[5]

Bieth J, 1986, REGULATION MATRIX AC, P217

[6]

BIGNON J, 1976, AM REV RESPIR DIS, V113, P109

[7]

BOSWELL DR, 1986, TRENDS BIOCHEM SCI, V11, P103

[8]

BROGARD JM, 1985, DRUG EXP CLIN RES, V11, P397

[9] STRUCTURE AND VARIATION OF HUMAN ALPHA-1-ANTITRYPSIN [J].

CARRELL, RW ;

JEPPSSON, JO ;

LAURELL, CB ;

BRENNAN, SO ;

OWEN, MC ;

VAUGHAN, L ;

BOSWELL, DR .

NATURE, 1982, 298 (5872) :329-334

[10] AUGMENTATION OF LUNG ANTINEUTROPHIL ELASTASE CAPACITY WITH RECOMBINANT HUMAN ALPHA-1-ANTITRYPSIN [J].

CASOLARO, MA ;

FELLS, G ;

WEWERS, M ;

PIERCE, JE ;

OGUSHI, F ;

HUBBARD, R ;

SELLERS, S ;

FORSTROM, J ;

LYONS, D ;

KAWASAKI, G ;

CRYSTAL, RG .

JOURNAL OF APPLIED PHYSIOLOGY, 1987, 63 (05) :2015-2023

← 1 2 3 4 5 →