CATION-INDUCED EFFLUX OF CALCIUM FROM THE MITOCHONDRIA OF HYMENOLEPIS-DIMINUTA

被引：2

作者：

WANI, JH

SIDDIQUI, A

SRIVASTAVA, VML

机构：

[1] MD ANDERSON CANC CTR,DEPT CLIN INVEST,HOUSTON,TX 77030

[2] CENT DRUG RES INST,DIV BIOCHEM,LUCKNOW 226001,UTTAR PRADESH,INDIA

来源：

CELL BIOCHEMISTRY AND FUNCTION | 1995年 / 13卷 / 03期

关键词：

CALCIUM; EFFLUX; TRANSPORT; HYMENOLEPIS DIMINUTA; CESTODA; MITOCHONDRIA;

D O I：

10.1002/cbf.290130314

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have previously reported that Ca2+ influx into the mitochondria of Hymenolepis diminuta, a rat intestinal cestode, takes place through an electrophoretic uniport system. Sodium and lithium were found to induce efflux of Ca-45(2+) from the mitochondria of H. diminuta. The two cations induced the efflux in a hyperbolic and linear fashion, respec tivity. The efflux as well as an exchange of external Ca2+ with internal Ca-45(2+) was inhibited by lanthanum. The type of Ca2+ transport system in the cestode organelle has been discussed and compared with that of the host (mammalian) counterpart.

引用

页码：227 / 230

页数：4

共 19 条

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[2]

BRAND MD, 1976, J BIOL CHEM, V251, P968

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