BIOCHEMICAL RESPONSES OF BROILER CHICKS TO FOLATE-DEFICIENCY

被引：3
|
作者：
RENNIE, JS
WHITEHEAD, CC
ARMSTRONG, J
机构：
[1] AFRC Institute of Animal Physiology and Genetics Research, Edinburgh Research Station, Midlothian, EH25 9PS, Roslin
来源：
BRITISH JOURNAL OF NUTRITION | 1993年 / 69卷 / 03期
关键词：
FOLIC ACID; DIHYDROFOLATE REDUCTASE; DEOXYURIDINE SUPPRESSION; PHOSPHORIBOSYLPYROPHOSPHATE; CHICKEN;
D O I：
10.1079/BJN19930080
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
The effects of folate sufficiency and deficiency in three pathways of folate metabolism were studied in 2- and 3-week-Old broiler chicks. Erythrocyte phosphoribosylpyrophosphate concentrations and dihydrofolate reductase (EC 1.5.1.3) activity were significantly elevated in folate deficiency. Percentage incorporation of deoxyuridine into bone marrow DNA was reduced in folate deficiency. There was a trend towards reduced liver dihydrofolate reductase activity in deficient chicks. These studies identify further biochemical criteria that can be used to assess folate status of chicks.
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页码：801 / 808
页数：8
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