OPTIMIZATION OF ELECROSPINNING OF PVDF SCAFFOLDS FABRICATION USING RESPONSE SURFACE METHOD

被引:0
作者
Nallappan, Madana Leela [1 ]
Nasef, Mohamad Mahmoud [2 ]
机构
[1] Univ Teknol Malaysia, Fac Chem Engn, Johor Baharu 81310, Johor, Malaysia
[2] Univ Teknologi Malaysia Jalan Semarak, Malaysia Japan Int Inst Technol, Int Campus, Kuala Lumpur 54000, Malaysia
来源
JURNAL TEKNOLOGI | 2015年 / 75卷 / 06期
关键词
Poly(vinylidene fluoride); electrospinning; optimization; response surface methodology; central composite design;
D O I
暂无
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Poly(vinylidene fluoride) (PVDF) scaffolds were prepared via electrospinning. The response surface methodology (RSM) was used to optimize the parameters that influence the average fibre diameter. The objective is to produce fibres with small diameters. The factors considered for experimental design were the applied electric voltage, the PVDF solution concentration, and the distance between the needle tip and the collecting drum. The Central Composite Design (CCD) was used to generate the experimental design whilst the analysis of variance (ANOVA) was performed to obtain statistical validation of regression models and to study the interaction between input parameters. The optimum operating conditions that guaranteed PVDF scaffolds with small nanofibre diameter were in the voltage and concentration range of 16-20 kV and 10-14wt%.
引用
收藏
页码:103 / 107
页数:5
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