3-Nitrophenylboronic acid-catalyzed efficient one-pot synthesis of 1,4-dihydropyridines and polyhydroquinolines

被引：11

作者：

Adude, Ramkishan N. ^{[1
]}

Tigote, Ramkishan M. ^{[1
]}

Goswami, Santosh V. ^{[1
]}

Bhusare, Sudhakar R. ^{[1
]}

机构：

[1] Dnyanopasak Coll, Dept Chem, Parbhani 431401, MS, India

来源：

INTERNATIONAL JOURNAL OF INDUSTRIAL CHEMISTRY | 2012年 / 3卷 / 01期

关键词：

1,4-dihydropyridines; Hantzsch condensation; Multi-component reactions; 3-nitrophenylboronic acid; Polyhydroquinolines;

D O I：

10.1186/2228-5547-3-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient protocol for the synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives via multi- component coupling reaction of aldehyde, beta-keto ester and ammonium acetate at room temperature condition using 3-nitrophenylboronic acid as a catalyst is described.

引用

页码：1 / 3

页数：3

共 24 条

[1]

Anderson DR, 2004, PCT INT APPL, Patent No. WO 2004055015 Al 20040701

[2]

Chen H, 2005, CHEN H, Patent No. WO 2005058315 Al 20050630

[3] 1,4-DIHYDROPYRIDINES - EFFECTS OF CHIRALITY AND CONFORMATION ON THE CALCIUM-ANTAGONIST AND CALCIUM AGONIST ACTIVITIES [J].

GOLDMANN, S ;

STOLTEFUSS, J .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1991, 30 (12) :1559-1578

[4]

Hantzsch A., 1882, LIEBIGS ANN CHEM, V215, P1, DOI DOI 10.1002/JLAC.18822150102

[5]

Harada H, 2002, HARADA H, Patent No. WO 2002006237 Al 20020124

[6] Novel solid-state synthesis of dimeric 4-aryl-1,4-dihydropyridines [J].

Hilgeroth, A ;

Heinemann, FW .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1998, 35 (02) :359-364

[7] Synthesis and biological evaluation of the first N-alkyl cage dimeric 4-aryl-1,4-dihydropyridines as novel nonpeptidic HIV-1 protease inhibitors [J].

Hilgeroth, A ;

Wiese, M ;

Billich, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (22) :4729-4732

[8] Rotameric properties of novel N-acyl and N-acyloxy dimeric 4-phenyl-1,4-dihydropyridines derived from developed solid-state synthesis [J].

Hilgeroth, A ;

Baumeister, U ;

Heinemann, F .

HETEROCYCLES, 1999, 51 (10) :2367-2376

[9]

Hilgeroth A, 2000, EUR J ORG CHEM, V2000, P245

[10]

Hilgeroth A, 1998, EUR J ORG CHEM, V1998, P1213

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