DESMETHYLDIAZEPAM KINETICS AFTER INTRAVENOUS, INTRAMUSCULAR, AND ORAL-ADMINISTRATION OF CLORAZEPATE DIPOTASSIUM

被引：21

作者：

OCHS, HR ^{[1
]}

STEINHAUS, E ^{[1
]}

LOCNISKAR, A ^{[1
]}

KNUCHEL, M ^{[1
]}

GREENBLATT, DJ ^{[1
]}

机构：

[1] TUFTS UNIV,NEW ENGLAND MED CTR,DIV CLIN PHARMACOL,BOSTON,MA 02111

来源：

KLINISCHE WOCHENSCHRIFT | 1982年 / 60卷 / 08期

关键词：

D O I：

10.1007/BF01735933

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：411 / 415

页数：5

共 12 条

[1] CHANGES IN ORAL ABSORPTION CHARACTERISTICS IN MAN OF DIPOTASSIUM CLORAZEPATE AT NORMAL AND ELEVATED GASTRIC PH [J].

ABRUZZO, CW ;

MACASIEB, T ;

WEINFELD, R ;

RIDER, JA ;

KAPLAN, SA .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1977, 5 (04) :377-390

[2] DESMETHYLDIAZEPAM KINETICS IN THE ELDERLY AFTER ORAL PRAZEPAM [J].

ALLEN, MD ;

GREENBLATT, DJ ;

HARMATZ, JS ;

SHADER, RI .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1980, 28 (02) :196-202

[3] DETERMINATION OF CHLORAZEPATE AND ITS MAJOR METABOLITES IN BLOOD AND URINE BY ELECTRON-CAPTURE GAS-LIQUID-CHROMATOGRAPHY [J].

BROOKS, MA ;

HACKMAN, MR ;

WEINFELD, RE ;

MACASIEB, T .

JOURNAL OF CHROMATOGRAPHY, 1977, 135 (01) :123-131

[4] ENTRY OF DIAZEPAM AND ITS MAJOR METABOLITE INTO CEREBROSPINAL-FLUID [J].

GREENBLATT, DJ ;

OCHS, HR ;

LLOYD, BL .

PSYCHOPHARMACOLOGY, 1980, 70 (01) :89-93

[5] DETERMINATION OF DESMETHYLDIAZEPAM IN PLASMA BY ELECTRON-CAPTURE GLC - APPLICATION TO PHARMACOKINETIC STUDIES OF CLORAZEPATE [J].

GREENBLATT, DJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1978, 67 (03) :427-429

[6]

GREENBLATT DJ, 1981, BRIT J CLIN PHARMACO, V11, pS11

[7]

GREENBLATT DJ, 1980, J PHARMACOL EXP THER, V215, P86

[8] EFFECT OF AGE AND BILLROTH GASTRECTOMY ON ABSORPTION OF DESMETHYLDIAZEPAM FROM CLORAZEPATE [J].

OCHS, HR ;

GREENBLATT, DJ ;

ALLEN, MD ;

HARMATZ, JS ;

SHADER, RI ;

BODEM, G .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1979, 26 (04) :449-456

[9]

OCHS HR, 1978, J PHARMACOL EXP THER, V205, P516

[10]

SHADER RI, 1978, CLIN PHARMACOL THER, V24, P308

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