HYPERTHYROIDISM SECONDARY TO A PITUITARY-ADENOMA SECRETING TSH, FSH, ALPHA-SUBUNIT AND GH

被引：14
作者：
PATRICK, AW
ATKIN, SL
MACKENZIE, J
FOY, PM
WHITE, NC
MACFARLANE, IA
机构：
[1] WALTON HOSP,DEPT ENDOCRINOL,LIVERPOOL,ENGLAND
[2] WALTON HOSP,DEPT NEUROL SCI,LIVERPOOL,ENGLAND
[3] UNIV LIVERPOOL,ROYAL LIVERPOOL HOSP,DEPT MED,LIVERPOOL L69 3BX,ENGLAND
来源：
CLINICAL ENDOCRINOLOGY | 1994年 / 40卷 / 02期
关键词：
D O I：
10.1111/j.1365-2265.1994.tb02480.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 51-year-old man had been treated for hyperthyroidism with antithyroid drugs for 8 years. He was then found to have a large pituitary adenoma with biochemical evidence of overproduction of TSH, FSH and alpha-subunit. Subsequent immunocytochemical and tissue culture studies confirmed secretion of these hormones. In addition, the tumour stained for GH and was capable of GH production in vitro. This combination of hormones produced by a pituitary adenoma has not been previously reported.
引用
收藏
页码：275 / 278
页数：4
相关论文
共 12 条
[1]  
ATKIN SL, 1993, IN VITRO CELL DEV-AN, V29A, P1
[2]   TREATMENT OF HYPERTHYROIDISM DUE TO INAPPROPRIATE SECRETION OF THYROTROPIN WITH THE SOMATOSTATIN ANALOG SMS 201-995 [J].
BECKPECCOZ, P ;
MARIOTTI, S ;
GUILLAUSSEAU, PJ ;
MEDRI, G ;
PISCITELLI, G ;
BERTOLI, A ;
BARBARINO, A ;
RONDENA, M ;
CHANSON, P ;
PINCHERA, A ;
FAGLIA, G .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1989, 68 (01) :208-214
[3]   RESPONSE OF THYROTROPIN-SECRETING PITUITARY-ADENOMAS TO A LONG-ACTING SOMATOSTATIN ANALOG [J].
COMI, RJ ;
GESUNDHEIT, N ;
MURRAY, L ;
GORDEN, P ;
WEINTRAUB, BD .
NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (01) :12-17
[4]   EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN PROXIMAL TUBULES OF MOUSE KIDNEY - ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE [J].
GRAHAM, RC ;
KARNOVSKY, MJ .
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1966, 14 (04) :291-+
[5]   HYPERTHYROIDISM DUE TO THYROTROPIN-PRODUCING PITUITARY CHROMOPHOBE ADENOMA [J].
HAMILTON, CR ;
ADAMS, LC ;
MALOOF, F .
NEW ENGLAND JOURNAL OF MEDICINE, 1970, 283 (20) :1077-&
[6]  
JONES RE, 1985, P AM COLLEGE PHYSICI, P46
[7]   HYPERTHYROIDISM CAUSED BY A PITUITARY THYROTROPHIN-SECRETING TUMOR WITH EXCESSIVE SECRETION OF THYROTROPHIN-RELEASING HORMONE AND SUBSEQUENTLY FOLLOWED BY GRAVES-DISEASE IN A MIDDLE-AGED WOMAN [J].
KAMOI, K ;
MITSUMA, T ;
SATO, H ;
YOKOYAMA, M ;
WASHIYAMA, K ;
TANAKA, R ;
ARAI, O ;
TAKASU, N ;
YAMADA, T .
ACTA ENDOCRINOLOGICA, 1985, 110 (03) :373-382
[8]   A CASE OF PITUITARY-ADENOMA WITH POSSIBLE SIMULTANEOUS SECRETION OF THYROTROPIN AND FOLLICLE-STIMULATING-HORMONE [J].
KOIDE, Y ;
KUGAI, N ;
KIMURA, S ;
FUJITA, T ;
KAMEYA, T ;
AZUKIZAWA, M ;
OGATA, E ;
TOMONO, Y ;
YAMASHITA, K .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1982, 54 (02) :397-403
[9]   RESPONSE OF A GH-SECRETING AND TSH-SECRETING PITUITARY-ADENOMA TO A SOMATOSTATIN ANALOG (SMS 201-995) - EVIDENCE THAT GH AND TSH COEXIST IN THE SAME CELL AND SECRETORY GRANULES [J].
MALARKEY, WB ;
KOVACS, K ;
ODORISIO, TM .
NEUROENDOCRINOLOGY, 1989, 49 (03) :267-274
[10]   THYROTROPIN-SECRETING PITUITARY-TUMORS [J].
SMALLRIDGE, RC .
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1987, 16 (03) :765-792
12