VDJ RECOMBINATION

被引:344
作者
ALT, FW
OLTZ, EM
YOUNG, F
GORMAN, J
TACCIOLI, G
CHEN, J
机构
来源
IMMUNOLOGY TODAY | 1992年 / 13卷 / 08期
关键词
D O I
10.1016/0167-5699(92)90043-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The ability of lymphocyte receptor V, D and J gene segments to rearrange generates much of the receptor diversity that is the hallmark of the immune system. Naturally, the mechanisms of immunoglobulin and T-cell receptor gene recombination are of enormous interest. Here, Fred Alt and colleagues review current understanding of the process and speculate on future findings.
引用
收藏
页码:306 / 314
页数:9
相关论文
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