Advances in the management of MS symptoms: recently proposed clinical management algorithms

被引:4
作者
Vermersch, Patrick [1 ]
机构
[1] Univ Lille, Hop Roger Salengro, CHU Lille, Dept Neurol, F-59037 Lille, France
关键词
algorithms; multiple sclerosis; review; Sativex; spasticity management guidelines; THC:CBD oromucosal spray;
D O I
10.2217/nmt.15.57
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Guidelines from both the German and Spanish Neurology Societies for managing patients with multiple sclerosis (MS) spasticity emphasize the importance of setting clear objectives and use evidence levels and grades to support their recommendations. Swedish guidelines for MS spasticity also reflect the need to establish treatment aims and recommend use of validated scales to measure symptom changes. Treatment of generalized MS spasticity, beyond physiotherapy, tends to begin with baclofen, tizanidine and/or diazepam, adding Sativex (THC:CBD) oromucosal spray for moderate-to-severe cases. The European Federation of Neurological Societies/European Academy of Neurology Taskforce on Spasticity in Multiple Sclerosis is currently reviewing the literature supporting the pharmacological treatment of MS spasticity and aims to publish recommendations in the near future to guide clinicians in their treatment choices.
引用
收藏
页码:23 / 26
页数:4
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