Clinical Guidelines on Long-Term Pharmacotherapy for Bipolar Disorder in Children and Adolescents

被引:8
作者
Cox, Joanna H. [1 ,2 ]
Seri, Stefano [3 ]
Cavanna, Andrea E. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Univ Birmingham, Dept Neuropsychiat, Birmingham B15 2FG, W Midlands, England
[2] BSMHFT, Birmingham B15 2FG, W Midlands, England
[3] Aston Univ, Sch Life & Hlth Sci, Birmingham B4 7ET, W Midlands, England
[4] Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London WC1N 3BG, England
[5] UCL, London WC1N 3BG, England
关键词
adolescents; bipolar disorder; children; guidelines; pharmacotherapy;
D O I
10.3390/jcm3010135
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bipolar disorder is a severe affective disorder which can present in adolescence, or sometimes earlier, and often requires a pharmacotherapeutic approach. The phenomenology of bipolar disorder in children and adolescents appears to differ from that of adult patients, prompting the need for specific pharmacotherapy guidelines for long-term management in this patient population. Current treatment guidelines were mainly developed based on evidence from studies in adult patients, highlighting the requirement for further research into the pharmacotherapy of children and adolescents with bipolar disorder. This review compares and critically analyzes the available guidelines, discussing the recommended medication classes, their mechanisms of action, side effect profiles and evidence base.
引用
收藏
页码:135 / 143
页数:9
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