Heart Failure in East Asia

被引：72

作者：

Guo, Yutao ^{[1
,2
]}

Lip, Gregory Y. H. ^{[2
]}

Banerjee, Amitava ^{[1
]}

机构：

[1] Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham, W Midlands, England

[2] Chinese Peoples Liberat Army Gen Hosp, Dept Geriatr Cardiol, Beijing, Peoples R China

来源：

CURRENT CARDIOLOGY REVIEWS | 2013年 / 9卷 / 02期

关键词：

Heart failure; epidemiology; management; East Asia;

D O I：

10.2174/1573403X11309020004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure (HF) carries a major burden of disease in East Asia, with high associated risk of mortality and morbidity. In recent decades, the epidemiology of HF has changed with social and economical development in East Asia. The burden of HF is still severe in East Asia. The prevalence of HF ranges from 1.3% to 6.7% throughout the region. As aetiological factors, ischaemic heart disease has increased and valvular disease reduced in most East Asian countries. Diuretics are the most commonly used drugs (51.0%-97%), followed by renin-angiotensin system (RAS) inhibitors (59%-77%), with angiotensin-converting enzyme inhibitors, ACEI, (32%-52%) and has angiotensin-2 receptor blockers, ARBs (31%-44%) in similar proportions. Beta-blocker use has also increased in recent years. Total mortality from HF ranges from 2% to 9% in China, Taiwan, Singapore, Thailand, and Japan. Age>65 years, diabetes mellitus, anaemia, renal dysfunction and atrial fibrillation (AF) are associated with adverse outcome. More prospective, region-specific data are still required, particularly regarding new drug therapies such as eplerenone and ivabradine.

引用

页码：112 / 122

页数：11

共 60 条

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