ANTIINFLAMMATORY 1-PHENYLPYRAZOLE-4-HETEROARYLALKANOIC ACIDS

被引：21

作者：

GODDARD, CJ

机构：

[1] Department of Medicinal Chemistry, Pfizer Central Research, Groton, Connecticut

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 06期

关键词：

D O I：

10.1002/jhet.5570280625

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of antiinflammatory agents, based on the structural integration of fentiazac and lonazolac, was synthesized.

引用

页码：1607 / 1612

页数：6

共 15 条

[1] NONAQUEOUS DIAZOTIZATION OF 5-AMINO-1-ARYL-1H-PYRAZOLE-4-CARBOXYLATE ESTERS [J].

BECK, JR ;

GAJEWSKI, RP ;

LYNCH, MP ;

WRIGHT, FL .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1987, 24 (01) :267-270

[2]

BOLTZE KH, 1980, ARZNEIMITTEL-FORSCH, V30-2, P1314

[3] NONSTEROIDAL ANTIINFLAMMATORY AGENTS .1. 2,4-DIPHENYLTHIAZOLE-5-ACETIC ACID AND RELATED COMPOUNDS [J].

BROWN, K ;

CATER, DP ;

CAVALLA, JF ;

GREEN, D ;

NEWBERRY, RA ;

WILSON, AB .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (11) :1177-1181

[4] POTENTIAL PURINE ANTAGONISTS .6. SYNTHESIS OF 1-ALKYL-4-SUBSTITUTED AND 1-ARYL-4-SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDINES [J].

CHENG, CC ;

ROBINS, RK .

JOURNAL OF ORGANIC CHEMISTRY, 1956, 21 (11) :1240-1256

[5] AMINOCYANOPYRAZOLES [J].

DICKINSON, CL ;

MCKUSICK, BC ;

WILLIAMS, JK .

JOURNAL OF ORGANIC CHEMISTRY, 1964, 29 (07) :1915-&

[6] REACTIONS OF SOME UNSATURATED PYRAZOLE COMPOUNDS [J].

FINAR, IL ;

SAUNDERS, KJ .

JOURNAL OF THE CHEMICAL SOCIETY, 1963, (AUG) :3967-&

[7]

FINAR IL, 1957, J CHEM SOC, P3314

[8] 5-HETEROARYL-2-THIOPHENECARBOXYLIC ACIDS - OXAZOLES AND OXADIAZOLES [J].

GODDARD, CJ .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1991, 28 (01) :17-28

[9]

Hantzsch A, 1888, BER DTSCH CHEM GES, V21, P938

[10] 1,3-DIPOLAR CYCLOADDITIONS .36. PYRAZOLES FROM SYDNONES AND ALPHA BETA-UNSATURATED NITRILES OR CARBONYL COMPOUNDS [J].

HUISGEN, R ;

GRASHEY, R ;

GOTTHARD.H .

CHEMISCHE BERICHTE-RECUEIL, 1968, 101 (03) :829-&

← 1 2 →