A SELECTIVE PROTECTION OF 2,3-DIAMINOPROPIONIC ACID

被引：15

作者：

EGBERTSON, MS

HOMNICK, CF

HARTMAN, GD

机构：

[1] Department of Medicinal Chemistry, Merck Research Laboratories, West Point

来源：

SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 05期

关键词：

D O I：

10.1080/00397919308009829

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A two step selective protection of 2,3-diaminopropionic acid yields the useful diaminopropionic acid methyl ester 3a. Further manipulation yields 2(S)-(N-benzyloxycarbonylamino)-3-aminopropionic acid methyl ester hydrochloride 5 in >99.9%ee.

引用

页码：703 / 709

页数：7

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