Glucose-sensitive insulin-releasing molecular systems

被引：18
|
作者：
Imanishi, Y
Ito, Y
机构：
[1] Division of Material Chemistry, Faculty of Engineering Kyoto University, Kyoto
来源：
PURE AND APPLIED CHEMISTRY | 1995年 / 67卷 / 12期
关键词：
D O I：
10.1351/pac199567122015
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three types of molecular systems for insulin release in response to glucose were designed and synthesized. i) Chemical valve was synthesized by immobilization of glucose oxidase onto poly(acrylic acid)-grafted porous membrane. ii) Membrane device was constructed by immobilization of insulin through disulfide linkage with combination of glucose dehydrogenase and electron mediators. iii) Enzyme device was made by coupling glucose oxidase and insulin through disulfide linkage.
引用
收藏
页码：2015 / 2021
页数：7
相关论文
共 50 条
  • [1] ENZYME MODIFICATION FOR GLUCOSE-SENSITIVE INSULIN-RELEASING SYSTEM
    ITO, Y
    CHUNG, DJ
    IMANISHI, Y
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1992, 204 : 213 - POLY
  • [2] SYNTHESIS OF GLUCOSE-SENSITIVE INSULIN-RELEASING PROTEIN DEVICES
    CHUNG, DJ
    ITO, Y
    IMANISHI, Y
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1994, 67 (05) : 1468 - 1471
  • [3] AN INSULIN-RELEASING SYSTEM THAT IS RESPONSIVE TO GLUCOSE
    ITO, Y
    CASOLARO, M
    KONO, K
    IMANISHI, Y
    JOURNAL OF CONTROLLED RELEASE, 1989, 10 (02) : 195 - 203
  • [4] Is there a future in glucose-sensitive, responsive insulin delivery systems?
    Peppas, NA
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2004, 14 (04): : 247 - 256
  • [5] Review: Glucose-sensitive insulin
    Hoeg-Jensen, Thomas
    MOLECULAR METABOLISM, 2020, 46
  • [6] Glucose-Sensitive Hydrogel Systems
    Valuev, I. L.
    Vanchugova, L. V.
    Valuev, L. I.
    POLYMER SCIENCE SERIES A, 2011, 53 (05) : 385 - 389
  • [7] Glucose-sensitive hydrogel systems
    I. L. Valuev
    L. V. Vanchugova
    L. I. Valuev
    Polymer Science Series A, 2011, 53 : 385 - 389
  • [8] Glucose-sensitive insulin with attenuation of hypoglycaemia
    Hoeg-Jensen, Thomas
    Kruse, Thomas
    Brand, Christian L.
    Sturis, Jeppe
    Fledelius, Christian
    Nielsen, Peter K.
    Nishimura, Erica
    Madsen, Alice R.
    Lykke, Lennart
    Halskov, Kim S.
    Koscova, Simona
    Kotek, Vladislav
    Davis, Anthony P.
    Tromans, Robert A.
    Tomsett, Michael
    Penuelas-Haro, Guillem
    Leonard, Daniel J.
    Orchard, Michael G.
    Chapman, Andy
    Invernizzi, Gaetano
    Johansson, Eva
    Granata, Daniele
    Hansen, Bo F.
    Pedersen, Thomas A.
    Kildegaard, Jonas
    Pedersen, Karen-Margrethe
    Refsgaard, Hanne H. F.
    Alifrangis, Lene
    Fels, Johannes J.
    Neutzsky-Wulff, Anita V.
    Sauerberg, Per
    Slaaby, Rita
    NATURE, 2024, : 944 - 951
  • [9] Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions
    Traitel, T
    Cohen, Y
    Kost, J
    BIOMATERIALS, 2000, 21 (16) : 1679 - 1687
  • [10] PROTEIN DEVICE FOR GLUCOSE-SENSITIVE RELEASE OF INSULIN
    ITO, Y
    IMANISHI, Y
    POLYMERIC DRUGS AND DRUG ADMINISTRATION, 1994, 545 : 47 - 54
12345