LONG-TERM MASS-SCREENING IN UTERINE CERVICAL-CARCINOMA ERADICATION STRATEGY

被引：1
作者：
SHIROMIZU, K [1 ]
OGAWA, M [1 ]
KAMATA, H [1 ]
TOMINAGA, K [1 ]
KOYAMA, Y [1 ]
机构：
[1] TOCHIGI CANC CTR,DIV GYNECOL,UTSUNOMIYA,TOCHIGI 320,JAPAN
来源：
JAPANESE JOURNAL OF CLINICAL ONCOLOGY | 1990年 / 20卷 / 02期
关键词：
MASS SCREENING; CERVICAL CARCINOMA; EARLY DETECTION;
D O I：
10.1093/oxfordjournals.jjco.a039377
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Results of the Tochigi Cancer Detection Center screening of a total of 252,453 women for uterine cervical neoplasm, conducted over fifteen years, are reported. Among the women, 16,454 (6.5%) were referred for precision reexamination and 14,129 (85.9%) responded. Eighty-nine patients with unmistakably invasive carcinomas at International Federation of Gynecology and Obstetrics (FIGO) Stage lb or more, 81 with microinvasive carcinomas at Stage la and 192 with carcinomas in situ were found, all of them receiving appropriate treatment. The cervical neoplasm detection rate decreased from 26.2 per 10,000 to 6.9 per 10,000 during the 15 years (average rate, 0.15%) with a relatively increasing trend of early stage carcinoma (microinvasive and in situ carcinomas) (62.9-84.0%) over frank carcinoma (37.1-16.0%). During the same period, the ratio of the uterine carcinoma mortality rate to that of all carcinomas decreased from 5.0 to 2.7%. The mean ages (years) of patients with frankly invasive (53.4), microinvasive (48.2) and in situ (45.6) carcinomas, however, remained constant over the 15 years. Five-year actuarial survival rates were 86.6% for frank, 98.8% for microinvasive and 98.8% for in situ carcinomas. Among rechecked women, all frank carcinoma patients were rescreened after more than one-and-a-half years of their last check. These results suggest that long-term mass screening and yearly checks would be of value both for detecting uterine carcinoma earlier and for reducing its mortality rate.
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页码：134 / 138
页数：5
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共 11 条
  • [1] Bain R.W., Crocker D.W., Rapid onset of cervical cancer in an upper socioeconomic group, Am. J. Obstet. Gynecol, 146, pp. 366-371, (1983)
  • [2] Dunn J.E., Schweitzer V., The relationship of cervical cytology to the incidence of invasive cervical cancer and mortality in Alameda County, California, 1960 to 1974, Am. J. Obstet. Gynecol, 139, pp. 868-876, (1981)
  • [3] Iwanari O., Appropriate frequency of mass screening for uterine cervical carcinoma, Nippon Sanka Fujinka Gakkai Zasshi, 39, pp. 1799-1805, (1987)
  • [4] Vital Statistics, 1986, (1987)
  • [5] Health Check Manual, (1987)
  • [6] Annual report of uterine cancer in Japan, Nippon Sanka Fujinka Gakkai Zasshi, 40, pp. 271-310, (1988)
  • [7] Kurman R.J., Schiffman M.H., Lancaster W.D., Reid R., Jensen A.B., Temple G.F., Lorincz A.T., Analysis of individual human papillomavirus type in cervical neoplasia: A possible role for type 18 in rapid progression, Am. J. Obstet. Gynecol, 159, pp. 293-296, (1988)
  • [8] Marshburn P.B., Trofatter K.F., Recurrent condyloma acuminatum in women over age 40: Association with immunosuppression and malignant disease, Am J. Obstet. Gynecol, 159, pp. 429-433, (1988)
  • [9] Sadeghi S.B., Sadeghi A., Robboy S.J., Prevalence of dysplasia and cancer of the cervix in a nationwide, planned parenthood population, Cancer, 61, pp. 2359-2361, (1988)
  • [10] Yamazaki H., Oshima A., Murakami R., Endoh S., Ubukata T., A long-term follow-up study of patients with gastric cancer detected by mass screening, Cancer, 63, pp. 613-617, (1989)
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