MECHANISMS OF ACTION OF ECT IN PARKINSONS-DISEASE - POSSIBLE ROLE OF PINEAL MELATONIN

被引：6
|
作者：
SANDYK, R [1 ]
机构：
[1] NEW YORK STATE PSYCHIAT INST & HOSP,DEPT CLIN NEUROPSYCHIAT,NEW YORK,NY 10032
来源：
INTERNATIONAL JOURNAL OF NEUROSCIENCE | 1990年 / 50卷 / 1-2期
关键词：
ETC; Melatonin; Parkinson's disease; Pineal gland;
D O I：
10.3109/00207459008987159
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Recent clinical studies have suggested that electroconvulsive therapy (ECT) may be efficacious in the therapy of Parkinson's disease (PD). However, the mechanisms of action of ECT in PD are largely unknown. PD may be associated with reduction in the secretory activity of pineal melatonin, and the therapeutic efficacy of ECT in PD may be associated with an effect on the secretory activity of pineal melatonin. Further studies involving analysis of plasma melatonin levels and circadian release prior to and following ECT are needed more precisely to determine the role of pineal melatonin in PD and in the therapeutic efficacy of ETC in PD. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：83 / 94
页数：12
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