THE SNF/SWI FAMILY OF GLOBAL TRANSCRIPTIONAL ACTIVATORS

被引：230

作者：

CARLSON, M ^{[1
]}

LAURENT, BC ^{[1
]}

机构：

[1] SUNY HLTH SCI CTR,DEPT MICROBIOL & IMMUNOL,BROOKLYN,NY 11203

来源：

CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 03期

关键词：

D O I：

10.1016/0955-0674(94)90032-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The yeast SNF/SWI proteins have a global role in transcriptional activation. This set of five proteins assists many gene-specific activators, most likely by altering chromatin structure to relieve repression. Recent work shows that the SNF/SWI proteins function together in a multiprotein complex and that SNF2 has DNA-dependent ATPase activity. SNF/SWI homologs have now been identified in Drosophila, mice and humans, suggesting a conserved role in transcriptional activation.

引用

页码：396 / 402

页数：7

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