AN UPDATE ON THE RECOVERY OF [O-18]WATER DURING THE SYNTHESIS OF [F-18] FDG BY A SIMPLE MODIFICATION IN THE PROCEDURE

被引:0
作者
CHALY, T [1 ]
BANDYOPADHYAY, D [1 ]
MATACCHIERI, R [1 ]
MARGOULEFF, D [1 ]
机构
[1] CYCLOTRON PET RES DEPT,MANHASSET,NY 11030
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中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A simple procedural change for the synthesis of [F-18]FDG has been used to recover [O-18]water by direct distillation. The [O-18]water thus recovered is reusable to produce [F-18]fluoride without further purification. The recovery of [O-18]water is reliable and our results are based on over 300 routine FDG preparations. The [F-18]fluoride present in the target water is converted to potassium fluoride during the distillation and will be available for further reaction to complete the synthesis of FDG. The same procedure can be used to recover [O-18]water in similar situations where [F-18]fluoride is converted to potassium fluoride and in turn used to react with kryptofix for labeling other precursors.
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页码:1089 / 1091
页数:3
相关论文
共 14 条
[1]  
ALEXOFF D, 1989, APPL RADIAT ISOTOPES, V40, P1
[2]  
BURKE RJ, 1991, J NUCL MED, V32, pN13
[3]  
CHALY T, 1990, APPL RADIAT ISOTOPES, V41, P29
[4]  
HAMACHER K, 1986, J NUCL MED, V27, P235
[5]  
HAMACHER K, 1990, APPL RADIAT ISOTOPES, V41, P49
[6]  
HEISS WD, 1985, ATLAS POSITRON EMISS
[7]  
JEWETT MD, 1991, INT J APPL RADIAT IS, V42, P410
[8]   A SIMPLE O-18 WATER TARGET FOR F-18 PRODUCTION [J].
KILBOURN, MR ;
HOOD, JT ;
WELCH, MJ .
INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1984, 35 (07) :599-602
[9]  
LEVY S, 1982, J NUCL MED, V23, P918
[10]  
MULHOLLAND GK, 1991, APPL RADIAT ISOTOPES, V42, P1003