LACK OF ALLELIC POLYMORPHISM FOR THE MAJOR OUTER-MEMBRANE PROTEIN GENE OF THE AGENT OF GUINEA-PIG INCLUSION CONJUNCTIVITIS (CHLAMYDIA-PSITTACI)

被引：7

作者：

ZHAO, QX

SCHACHTER, J

STEPHENS, RS

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT LAB MED, SAN FRANCISCO, CA 94143 USA

[2] UNIV CALIF SAN FRANCISCO, FRANCIS I PROCTOR FDN, SAN FRANCISCO, CA 94143 USA

[3] UNIV CALIF BERKELEY, SCH PUBL HLTH, PROGRAM INFECT DIS, BERKELEY, CA 94720 USA

来源：

INFECTION AND IMMUNITY | 1993年 / 61卷 / 07期

关键词：

D O I：

10.1128/IAI.61.7.3078-3080.1993

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The major outer membrane protein gene (omp1) was sequenced for each of six Chlamydia Psittaci (guinea pig inclusion conjunctivitis [GPIC]) strains isolated from guinea pigs. Five of the isolates were obtained in the United States during the 1960s and 1970s, including the prototype strain isolated by Murray in 1962. The other isolate was obtained from a guinea pig in England. The nucleotide sequence of the omp1 gene for each strain was identical. The lack of omp1 allelic polymorphism among GPIC isolates suggests that, unlike C. trachomatis, the GPIC agent lacks antigenic variation in the major outer membrane protein.

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页码：3078 / 3080

页数：3

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