ANTI-HIV-1 ACTIVITY OF 2',3'-DIDEOXYNUCLEOSIDE ANALOGS - STRUCTURE-ACTIVITY RELATIONSHIP

被引：118
作者：
DECLERCQ, E
VANAERSCHOT, A
HERDEWIJN, P
BABA, M
PAUWELS, R
BALZARINI, J
机构：
来源：
NUCLEOSIDES & NUCLEOTIDES | 1989年 / 8卷 / 5-6期
关键词：
D O I：
10.1080/07328318908054206
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：659 / 671
页数：13
相关论文
共 27 条
[1]   BOTH 2',3'-DIDEOXYTHYMIDINE AND ITS 2',3'-UNSATURATED DERIVATIVE (2',3'-DI-DEOXYTHYMIDINENE) ARE POTENT AND SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION INVITRO [J].
BABA, M ;
PAUWELS, R ;
HERDEWIJN, P ;
DECLERCQ, E ;
DESMYTER, J ;
VANDEPUTTE, M .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 142 (01) :128-134
[2]   SELECTIVE-INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) BY 3'-AZIDO-2',3'-DIDEOXYGUANOSINE INVITRO [J].
BABA, M ;
PAUWELS, R ;
BALZARINI, J ;
HERDEWIJN, P ;
DECLERCQ, E .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 145 (03) :1080-1086
[3]   THE 2',3'-DIDEOXYRIBOSIDE OF 2,6-DIAMINOPURINE SELECTIVELY INHIBITS HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) REPLICATION INVITRO [J].
BALZARINI, J ;
PAUWELS, R ;
BABA, M ;
ROBINS, MJ ;
ZOU, R ;
HERDEWIJN, P ;
DECLERCQ, E .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 145 (01) :269-276
[4]   POTENT AND SELECTIVE ANTI-HTLV-III/LAV ACTIVITY OF 2',3'-DIDEOXYCYTIDINENE, THE 2',3'-UNSATURATED DERIVATIVE OF 2',3'-DIDEOXYCYTIDINE [J].
BALZARINI, J ;
PAUWELS, R ;
HERDEWIJN, P ;
DECLERCQ, E ;
COONEY, DA ;
KANG, GJ ;
DALAL, M ;
JOHNS, DG ;
BRODER, S .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (02) :735-742
[5]  
BALZARINI J, 1988, MOL PHARMACOL, V33, P243
[6]   ANTI-RETROVIRUS ACTIVITY OF 3'-FLUORO-SUBSTITUTED AND 3'-AZIDO-SUBSTITUTED PYRIMIDINE 2',3'-DIDEOXYNUCLEOSIDE ANALOGS [J].
BALZARINI, J ;
BABA, M ;
PAUWELS, R ;
HERDEWIJN, P ;
DECLERCO, E .
BIOCHEMICAL PHARMACOLOGY, 1988, 37 (14) :2847-2856
[7]  
BALZARINI J, 1987, MOL PHARMACOL, V32, P162
[8]   SYNTHESIS OF ENANTIOMERICALLY PURE CARBOCYCLIC 3'-AZIDO-2',3'-DIDEOXYTHYMIDINE, A POTENTIAL ANTI-AIDS DRUG [J].
BODENTEICH, M ;
GRIENGL, H .
TETRAHEDRON LETTERS, 1987, 28 (44) :5311-5312
[9]  
CAMARASA MJ, 1988, UNPUB NUCLEOSIDES NU
[10]   INHIBITORY EFFECT OF 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES ON INFECTIVITY, CYTOPATHIC EFFECTS, AND REPLICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS [J].
HAMAMOTO, Y ;
NAKASHIMA, H ;
MATSUI, T ;
MATSUDA, A ;
UEDA, T ;
YAMAMOTO, N .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (06) :907-910
123