Pharmacokinetic analysis

被引：0

作者：

Whiteley, William J. D. ^{[1
]}

Hardman, Jonathan G. ^{[2
,3
]}

机构：

[1] Nottingham Univ Hosp NHS Trust, Queens Med Ctr, Anaesthet, Nottingham, England

[2] Univ Hosp, Nottingham, England

[3] Univ Nottingham, Anaesthesia, Nottingham, England

来源：

ANAESTHESIA AND INTENSIVE CARE MEDICINE | 2011年 / 12卷 / 08期

关键词：

Clearance; compartmental; context-sensitive; half-life; pharmacokinetics;

D O I：

10.1016/j.mpaic.2011.05.009

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Pharmacokinetic analysis is an experimentally determined theory of how a drug behaves when in vivo. Volume of distribution, clearance and terminal half-life are defined. Compartmental modeling is introduced and some relevant graphs are described in this article. Applications of this theory in anaesthesia are considered.

引用

页码：365 / 367

页数：3