ANALYSIS OF HUMAN GROWTH-HORMONE GENE 5' SEQUENCES IN ISOLATED GROWTH-HORMONE DEFICIENCY PATIENTS

被引：2
|
作者：
WANG, YX [1 ]
YU, LL [1 ]
SHENG, Q [1 ]
MENG, CW [1 ]
SUN, J [1 ]
CHEN, SS [1 ]
机构：
[1] SHANGHAI MED UNIV 2,MOLEC BIOL LAB,SHANGHAI 200025,PEOPLES R CHINA
来源：
JOURNAL OF MEDICAL GENETICS | 1994年 / 31卷 / 01期
关键词：
D O I：
10.1136/jmg.31.1.81
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Human growth hormone (hGH) gene deletion (6.7 to 7.6 kb) is one of the causes of isolated growth hormone deficiency (IGHD), named IGHD IA. IGHD IA, however, only accounts for about 10% of the total IGHD patients. Most IGHD is caused by unknown mechanisms. Here, hGH gene 5' sequences in three IGHD patients without hGH gene deletion were analysed to see if there was any mutation hindering the expression of the hGH gene.
引用
收藏
页码：81 / 82
页数：2
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