MIGRAINE TO THE YEAR 2000

被引：11
作者：
SANDLER, M
机构：
[1] Department of Chemical Pathology, Queen Charlotte's and Chelsea Hospital, London
来源：
CEPHALALGIA | 1995年 / 15卷 / 04期
关键词：
D O I：
10.1046/j.1468-2982.1995.1504259.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Although migraine is inextricably bound up with 5-hydroxytryptamine and its many receptors, its precise mechanisms continue to elude us and there is still no clear evidence supporting either a vascular or neurogenic hypothesis unequivocally. What appears to distinguish migraine sufferers from normal subjects may be a greater genetic sensitivity to a wide variety of triggering agents-even including nitric oxide and the migraine aura, as well as those more usually recognized. Attention is drawn to a possible role for neurotrophins, such as the hyperalgesia-provoking nerve growth factor (NGF) in particular, as well as basic fibroblast growth factor (bFGF) and brain-derived neurotrophic factor (BDNF).
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页码：259 / 264
页数：6
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