ANTITUMOR ACTIVITIES OF ALPHA-MONOGALACTOSYLCERAMIDES, BETA-MONOGALACTOSYLCERAMIDES AND 4 DIASTEREOMERS OF AN ALPHA-GALACTOSYLCERAMIDE

被引：64

作者：

MOTOKI, K ^{[1
]}

KOBAYASHI, E ^{[1
]}

UCHIDA, T ^{[1
]}

FUKUSHIMA, H ^{[1
]}

KOEZUKA, Y ^{[1
]}

机构：

[1] KIRIN BREWERY CO LTD,PHARMACEUT RES LAB,TAKASAKI,GUMMA 37012,JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 07期

关键词：

D O I：

10.1016/0960-894X(95)00098-E

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We examined antitumor activities of alpha-, beta-monoglycosylceramides (MonoCers) and four diastereomers of an alpha-galactosylceramide (alpha-GalCer), and found that the alpha-GalCer among MonoCers and the 2S, 3R type among diastereomers show the strongest antitumor effects.

引用

页码：705 / 710

页数：6

共 13 条

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