Effect of Astragalus membranaceus extract on diabetic nephropathy

被引：24

作者：

Kim, Jiman ^{[1
]}

Moon, Eulsun ^{[2
]}

Kwon, Seungwon ^{[3
]}

机构：

[1] Kyunghee saeng Korean Med Clin, Seoul, South Korea

[2] Seoul 365 Med Clin, Seoul, South Korea

[3] Kyung Hee Univ, Coll Korean Med, Dept Cardiovasc & Neurol Dis, 1 Hoegi Dong,Dongdaemun Gu, Seoul 130702, South Korea

来源：

ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS | 2014年

关键词：

D O I：

10.1530/EDM-14-0063

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diabetic nephropathy, a microvascular complication of diabetes, is a progressive kidney disease caused by angiopathy of the capillaries in the kidney glomeruli. Herein, we report a case of a 62-year-old patient with a 30 year history of diabetes, who showed a substantial improvement in diabetic nephropathy on administration of 30 g of Astragalus membranaceus extract per day. After 1 month, estimated glomerular filtration rate increased from 47 to 72 ml/min per 1.73 m(2) and was subsequently maintained at the 1-month follow-up. Urinary protein levels also decreased following treatment. Herein, we present and discuss the evidence and mechanism of A. membranaceus on diabetic nephropathy in this patient.

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