There is now widespread recognition that relationships have important implications for health. To better understand this linkage, scholars have called for greater bridging between relationship science and the study of health. The goal of this paper is to raise awareness of another factor that needs to be incorporated into this area of study: culture. I recommend three steps that researchers can take to systematically incorporate culture into the study of relationships and health. First, I suggest four possible culture patterns to study: similarity, moderation, mediation, and novel constructs. Second, I suggest that theoretically meaningful cultural variation and multiple cultures be concurrently studied. The value of this strategy is highlighted via examples from three contexts that emphasize distinct approaches to self and emotion in relationships. Third, I suggest that key relationship processes in families and couples, two relationships with extensive implications for health, be studied. Selected studies of four relationship processes known to be relevant for health - expectations, formation and maintenance, emotions, and social support - are briefly reviewed to highlight the value of this focus. The theoretical and applied benefit of incorporating culture into the study of the association of relationships with health is discussed.