THE CAENORHABDITIS-ELEGANS GENE LIN-44 CONTROLS THE POLARITY OF ASYMMETRIC CELL DIVISIONS

被引：0

作者：

HERMAN, MA ^{[1
]}

HORVITZ, HR ^{[1
]}

机构：

[1] MIT,HOWARD HUGHES MED INST,DEPT BIOL,CAMBRIDGE,MA 02139

来源：

DEVELOPMENT | 1994年 / 120卷 / 05期

关键词：

C-ELEGANS; CELL LINEAGE; CELL POLARITY; POLARITY REVERSAL;

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The generation and orientation of cellular and organismic polarity are fundamental aspects of development. Mutations in the gene lin-44 of the nematode Caenorhabditis elegans reverse both the relative positions of specific sister cells and the apparent polarities of these cells. Thus, lin-44 mutants appear to generate polar cells but to misorient these cells along the body axis of the animal. We postulate that lin-44 acts to specify the orientation of polar cells.

引用

页码：1035 / 1047

页数：13

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