DISTINCT EXPRESSION OF 2 DROSOPHILA HOMOLOGS OF FIBROBLAST GROWTH-FACTOR RECEPTORS IN IMAGINAL DISKS

被引：19

作者：

EMORI, Y

SAIGO, K

机构：

[1] Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Bunkyo-ku, Tokyo, 113

来源：

FEBS LETTERS | 1993年 / 332卷 / 1-2期

关键词：

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; DROSOPHILA-MELANOGASTER; IMAGINAL DISC; IN-SITU HYBRIDIZATION;

D O I：

10.1016/0014-5793(93)80494-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The expression of two Drosophila homologs of FGF receptors (DRF1 and DRF2) in imaginal discs was studied. DFR1 mRNA was observed in several imaginal discs, whereas DFR2 mRNA was not detected. DFR1 expression in the wing and leg discs took place in probable myoblasts in a pattern similar to that of twist, a mesodermal gene. The mRNA was also detected in the morphogenetic furrow and its posterior region of the eye disc and around the proliferation center of the brain. These results suggest that DFR1 is involved in the development of mesodermal and neuronal cells constituting the adult body.

引用

页码：111 / 114

页数：4

共 17 条

[1] EXPRESSION OF A DOMINANT NEGATIVE MUTANT OF THE FGF RECEPTOR DISRUPTS MESODERM FORMATION IN XENOPUS EMBRYOS [J].