Sleep disturbance in mental health problems and neurodegenerative disease

被引:127
作者
Anderson, Kirstie N. [1 ]
Bradley, Andrew J. [2 ,3 ]
机构
[1] Newcastle Tyne Hosp NHS Trust, Dept Neurol, Newcastle Upon Tyne, Tyne & Wear, England
[2] Eli Lilly & Co Ltd, Lilly House, Basingstoke, Hants, England
[3] Newcastle Univ, Inst Neurosci, Newcastle Upon Tyne, Tyne & Wear, England
关键词
sleep; mental health; neurodegenerative disorders; cognition;
D O I
10.2147/NSS.S34842
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Sleep has been described as being of the brain, by the brain, and for the brain. This fundamental neurobiological behavior is controlled by homeostatic and circadian (24-hour) processes and is vital for normal brain function. This review will outline the normal sleep-wake cycle, the changes that occur during aging, and the specific patterns of sleep disturbance that occur in association with both mental health disorders and neurodegenerative disorders. The role of primary sleep disorders such as insomnia, obstructive sleep apnea, and REM sleep behavior disorder as potential causes or risk factors for particular mental health or neurodegenerative problems will also be discussed.
引用
收藏
页码:61 / 75
页数:15
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