FUNCTIONAL MAGNETIC-RESONANCE-IMAGING IN MEDICINE AND PHYSIOLOGY

被引：155

作者：

MOONEN, CTW ^{[1
]}

VANZIJL, PCM ^{[1
]}

FRANK, JA ^{[1
]}

LEBIHAN, D ^{[1
]}

BECKER, ED ^{[1
]}

机构：

[1] NIH,BETHESDA,MD 20892

来源：

SCIENCE | 1990年 / 250卷 / 4977期

关键词：

D O I：

10.1126/science.2218514

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Magnetic resonance imaging (MRI) is a well-established diagnostic tool that provides detailed information about macroscopic structure and anatomy. Recent advances in MRI allow the noninvasive spatial evaluation of various biophysical and biochemical processes in living systems. Specifically, the motion of water can be measured in processes such as vascular flow, capillary flow, diffusion, and exchange. In addition, the concentrations of various metabolites can be determined for the assessment of regional regulation of metabolism. Examples are given that demonstrate the use of functional MRI for clinical and research purposes. This development adds a new dimension to the application of magnetic resonance to medicine and physiology.

引用

页码：53 / 61

页数：9