RATIONALE FOR DEVELOPMENT OF A SYNTHETIC VACCINE AGAINST PLASMODIUM-FALCIPARUM MALARIA

被引：373
作者：
ZAVALA, F
TAM, JP
HOLLINGDALE, MR
COCHRANE, AH
QUAKYI, I
NUSSENZWEIG, RS
NUSSENZWEIG, V
机构：
[1] ROCKEFELLER UNIV,NEW YORK,NY 10021
[2] BIOMED RES INST,ROCKVILLE,MD 20852
[3] UNIV GHANA,NOGUSHI MEM INST MED RES,IMMUNOL UNIT,LEGON,GHANA
[4] NYU,MED CTR,DEPT PATHOL,NEW YORK,NY 10021
来源：
SCIENCE | 1985年 / 228卷 / 4706期
关键词：
D O I：
10.1126/science.2409595
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：1436 / 1440
页数：5
相关论文
共 29 条
[1]   IMMUNIZATION OF MAN AGAINST SPOROZITE-INDUCED FALCIPARUM MALARIA [J].
CLYDE, DF ;
MOST, H ;
MCCARTHY, VC ;
VANDERBERG, JP .
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1973, 266 (03) :169-177
[2]  
CREIGHTON TE, 1983, PROTEINS STRUCTURE M, P199
[3]   STRUCTURE OF THE GENE ENCODING THE IMMUNODOMINANT SURFACE-ANTIGEN ON THE SPOROZOITE OF THE HUMAN MALARIA PARASITE PLASMODIUM-FALCIPARUM [J].
DAME, JB ;
WILLIAMS, JL ;
MCCUTCHAN, TF ;
WEBER, JL ;
WIRTZ, RA ;
HOCKMEYER, WT ;
MALOY, WL ;
HAYNES, JD ;
SCHNEIDER, I ;
ROBERTS, D ;
SANDERS, GS ;
REDDY, EP ;
DIGGS, CL ;
MILLER, LH .
SCIENCE, 1984, 225 (4662) :593-599
[4]   CLONING AND EXPRESSION IN ESCHERICHIA-COLI OF THE MALARIAL SPOROZOITE SURFACE-ANTIGEN GENE FROM PLASMODIUM-KNOWLESI [J].
ELLIS, J ;
OZAKI, LS ;
GWADZ, RW ;
COCHRANE, AH ;
NUSSENZWEIG, V ;
NUSSENZWEIG, RS ;
GODSON, GN .
NATURE, 1983, 302 (5908) :536-538
[5]   PRIMING FOR AND INDUCTION OF ANTI-POLIOVIRUS NEUTRALIZING ANTIBODIES BY SYNTHETIC PEPTIDES [J].
EMINI, EA ;
JAMESON, BA ;
WIMMER, E .
NATURE, 1983, 304 (5928) :699-703
[6]   DNA CLONING OF PLASMODIUM-FALCIPARUM CIRCUMSPOROZOITE GENE - AMINO-ACID-SEQUENCE OF REPETITIVE EPITOPE [J].
ENEA, V ;
ELLIS, J ;
ZAVALA, F ;
ARNOT, DE ;
ASAVANICH, A ;
MASUDA, A ;
QUAKYI, I ;
NUSSENZWEIG, RS .
SCIENCE, 1984, 225 (4662) :628-630
[7]   CIRCUMSPOROZOITE GENE OF PLASMOIDIUM-CYNOMOLGI (GOMBAK) - CDNA CLONING AND EXPRESSION OF THE REPETITIVE CIRCUMSPOROZOITE EPITOPE [J].
ENEA, V ;
ARNOT, D ;
SCHMIDT, EC ;
COCHRANE, A ;
GWADZ, R ;
NUSSENZWEIG, RS .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23) :7520-7524
[8]   IDENTIFICATION AND CHEMICAL SYNTHESIS OF A TANDEMLY REPEATED IMMUNOGENIC REGION OF PLASMODIUM-KNOWLESI CIRCUMSPOROZOITE PROTEIN [J].
GODSON, GN ;
ELLIS, J ;
SVEC, P ;
SCHLESINGER, DH ;
NUSSENZWEIG, V .
NATURE, 1983, 305 (5929) :29-33
[9]   NEUTRALIZATION OF THE INFECTIVITY OF SPOROZOITES OF PLASMODIUM-KNOWLESI BY ANTIBODIES TO A SYNTHETIC PEPTIDE [J].
GYSIN, J ;
BARNWELL, J ;
SCHLESINGER, DH ;
NUSSENZWEIG, V ;
NUSSENZWEIG, RS .
JOURNAL OF EXPERIMENTAL MEDICINE, 1984, 160 (03) :935-940
[10]  
HOLLINGDALE MR, 1984, J IMMUNOL, V132, P909
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